Glutathione Support via NAC
N-acetylcysteine (NAC), a cysteine precursor, has been the most common solution for Glutathione supplementation, particularly in therapeutic use for acetaminophen overdose. NAC supplements have been widely used as a method of action for delivering cysteine through the body’s digestive system and making it bio-available for cells.
Effective Cysteine supplementation, the use of products built upon NAC and other glutathione amino acid precursors like L-Glutamine, can be a viable option. While N-Acetyl Cysteine is likely safe for most adults, it has some drawbacks and negative side-effects may occur in certain individuals:
- NAC is easily oxidized and therefore requires larger doses to be effective.
- It is metabolized rapidly, resulting in a shorter half-life that requires multiple doses per day.
- It has an unpleasant sulfur smell.
- It can cause gastrointestinal issues, including nausea, vomiting, and diarrhea.
This warrants the need for additional means of endogenous Glutathione beyond NAC. One research team, after 25 years of researching more effective means of natural glutathione enhancement, developed a compound combining the amino acid L-cysteine with D-ribose in a patented formula. This unique fusion of cysteine and ribose has been shown to provide an advanced cysteine delivery system that supports endogenous glutathione levels while also supporting Adenosine triphosphate (ATP) production.
This patented, bonded compound was named RiboCeine®.